tecovirimat will improve the level or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Tecovirimat is usually a weak inhibitor of CYP2C8 and CYP2C19. Check for adverse outcomes if coadministered with sensitive substrates of such enzymes.I like that I have an immediate-use seizure medication I can use speedily,